[The genetic determinism of polygenic diseases].
نویسنده
چکیده
Progress in molecular biology has opened the way to identifying genes involved in predisposition to multigene diseases. The two methods currently used for this purpose--analysis of candidate genes and systematic genomic screening--have given interesting but only very partial results. The problem is complicated by the large number of genes involved, their low penetrance, and linkage disequilibrium.
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عنوان ژورنال:
- Bulletin de l'Academie nationale de medecine
دوره 189 5 شماره
صفحات -
تاریخ انتشار 2005